foolish and weak...

1 Corinthians 1:27  But God hath chosen the foolish things of the world to confound the wise; and God hath chosen the weak things of the world to confound the things which are mighty;

Here God calls those who are not necessarily wise, mighty, or noble according to the ways of the world. Instead, He takes ordinary people and gives them the wisdom and strength to extraordinary things.  This confounds or confuses those who consider themselves to be of high education, intellect, and position because of their pride. This is because pride, along with lust of the flesh and eyes, which is not of the Father, but is of the world (1 John 2:15-16). When this happens, believers are despised and persecuted (1 Corinthians 4:10; James 2:1-6; 2 Timothy 3:12) until such time as God sets things right forever.

the foolish and weak...

1 Corinthians 1:26 Brothers and sisters, think of what you were when you were called. Not many of you were wise by human standards; not many were influential; not many were of noble birth. 27 But God chose the foolish things of the world to shame the wise; God chose the weak things of the world to shame the strong. 28 God chose the lowly things of this world and the despised things--and the things that are not--to nullify the things that are, 29 so that no one may boast before him. 30 It is because of him that you are in Christ Jesus, who has become for us wisdom from God--that is, our righteousness, holiness and redemption. 31 Therefore, as it is written: 'Let the one who boasts boast in the Lord.'

Paul shows that God was pleased to save those who believed the "weak and foolish" gospel of Christ crucified. In fact, God intentionally chose those who were weak and foolish in the world's eyes to believe the "weak and foolish" gospel of Jesus. In this way, God will shame the supposed wisdom and strength of all those high-status people who have rejected faith in Christ (1 Corinthians 1:26–31).